Comparison of 3 T and 1.5 T for T2* magnetic resonance of tissue iron

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Comparison of 3 T and 1.5 T for T2* magnetic resonance of tissue iron

BACKGROUND T2* magnetic resonance of tissue iron concentration has improved the outcome of transfusion dependant anaemia patients. Clinical evaluation is performed at 1.5 T but scanners operating at 3 T are increasing in numbers. There is a paucity of data on the relative merits of iron quantification at 3 T vs 1.5 T. METHODS A total of 104 transfusion dependent anaemia patients and 20 normal...

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Evaluation of tissue doppler echocardiography and T2* magnetic resonance imaging in iron load of patients with thalassemia major

Background: Iron-mediated cardiomyopathy is the main complication of thalassemia major (TM) patients. Therefore, there is an important clinical need in the early diagnosis and risk stratification of patients. The aim of this study was to evaluate the efficacy of tissue doppler imaging (TDI) to study cardiac iron overload in patients with TM using T2* magnetic resonance (MR) as the gold-standard...

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On T2* magnetic resonance and cardiac iron.

BACKGROUND Measurement of myocardial iron is key to the clinical management of patients at risk of siderotic cardiomyopathy. The cardiovascular magnetic resonance relaxation parameter R2* (assessed clinically via its reciprocal, T2*) measured in the ventricular septum is used to assess cardiac iron, but iron calibration and distribution data in humans are limited. METHODS AND RESULTS Twelve h...

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As a clinician, it is important to never underestimate the power of basic science to deliver new answers to old questions. At the outset of the development of magnetic resonance (MR), scientists demonstrated differences in magnetic relaxation between normal and malignant tissues that were of significant interest, although only clinically exploited later through MR spectroscopy. Some 30 years on...

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ژورنال

عنوان ژورنال: Journal of Cardiovascular Magnetic Resonance

سال: 2016

ISSN: 1532-429X

DOI: 10.1186/s12968-016-0259-9